20% Whitening Gel Refills

Whiten up to 5 shades at home with Opalescence™ Whitening Gel Refills in a faster-acting 20% carbamide peroxide formula. For use with your dentist-provided custom tray.

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Our best Whitening Gel refill strength option for less-sensitive teeth and faster results. Fill your own custom tray or retainer with our dentist-created 20% carbamide peroxide formula for a brilliant smile in just days. Get quick results from wearing just a few hours per day. Brighten your smile up to 5 shades at home, safely & effectively.

We’re so confident you’ll love your smile after using our products, we offer a 30-Day Satisfaction Guarantee.

Vegan

Certified Gluten-Free

Certified Kosher

  1. Express one continuous line of gel along the lower half of the cheek side of each custom tray. Use 1⁄3 to 1⁄2 of syringe per arch.
  2. Lightly tap tray to adapt tray sides to teeth. Wear Opalescence 20% gel for 2–4 hours
  3. Remove excess gel with soft toothbrush. Do not swallow rinsed gel.
  4. Clean tray with soft brush and water.

Glycerin, Water (Aqua), Carbamide Peroxide, Xylitol, Carbomer, PEG-6, Sodium Hydroxide, Peppermint Oil, EDTA

  • Store in a cool place.
  • Do not use if you have a known allergy or sensitivity to listed ingredients. If allergic reaction is observed, rinse exposed area thoroughly with water and consult your physician.
  • Routine dental examinations are recommended prior to use.
  • Pregnant or nursing women and users with serious health concerns should consult their health care provider prior to treatment.
  • Not recommended for use by children under twelve years of age.
  • Avoid whitening gel contact with any soft tissue, including eyes. If gel contacts soft tissue, rinse the contacted area immediately and seek medical assistance if needed.
  • Some users may experience temporary discomfort of the gums, lips, throat, tongue, or teeth. Use of Opalescence Sensitivity Relief Toothpaste is recommended both before and after whitening. Should any of these symptoms persist or worsen after discontinuing use, contact your dentist. These side effects will usually subside within 1–3 days after discontinuing use.
  • Ingestion of small amounts of gel during use is expected. If large amounts of gel are ingested, drink large amounts of water and contact your healthcare provider. If gel is aspirated, seek immediate medical attention.
  • Do not eat, drink, smoke, or use tobacco products while whitening trays are in place.
  • Use only dentist-recommended trays with this product.
  • Stop whitening 7–10 days prior to any dental appointment.

Dentist-designed whitening gel refills


Customized to your smile

Fill your custom tray yourself for maximum whitening control

Whiten quickly & visibly

Can whiten teeth up to 5 shades

Gentle on teeth

Contains potassium nitrate for added comfort while whitening

Works on discolored teeth

Effectively lifts stains from coffee, wine, smoking, soda & more

How to use Opalescence™ Whitening Gel Refills

If you experience any significant sensitivity, stop your treatment and talk to your dentist.

Are Opalescence™ Whitening Gel Refills right for me?


  • Want to whiten quickly & safely
  • Already have a dentist-provided custom tray
  • Want options for sensitive teeth

Don’t have a custom tray?

Frequently Asked Questions

Reach out to your dentist for a pre-whitening consultation to discuss having a custom tray made—or try our convenient prefilled whitening trays.

Yes, Opalescence™ Whitening Gel Refills feature the same formulation as the product you buy from your dentist.

If you do not have any sensitivity of the gums or teeth, you can wear it daily for the recommended wear time in the instructions.

Just express one continuous bead of teeth whitening gel into trays, totaling approximately ⅓ to ½ of the syringe per tray. You can always refer to the instructions in your Opalescence™ Whitening Gel package.

Take a look at our Compare Page to see which formula is right for you. If you still have questions, we recommend visiting your dentist for a pre-whitening consultation to choose the option that best fits your needs.

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